Technological innovations in IVF gender selection: what you need to know
From embryo selection, genetic testing to AI-driven tools - how modern reproductive technologies are reshaping gender sex selection for nonmedical reasons
What is gender selection in IVF treatment?
For many couples and single women around the world, choosing the sex of their future child is not only an emotional decision, but also one that often leads to confusion, concern and a long search for reliable information. IVF gender selection – also known as sex selection through assisted reproductive technologies – is a process that allows intended parents to know the sex of the embryo before implantation.
Thanks to remarkable advances in genetic testing and embryo selection, today’s IVF patients have more clarity and control than ever before. Whether the goal is to reduce the risk of a genetic disorder, to balance the family, or simply to feel reassured during an emotional journey, modern technologies make it possible to make informed decisions – without needing a science degree to understand how it all works.
In this article, we’ll walk you through the most innovative and accurate methods used in IVF for gender selection, including preimplantation genetic testing (PGT), AI-supported embryo analysis, and why some older options like sperm sorting or microsort gender selection are no longer considered best practice. We’ll keep things clear and simple – while giving you the confidence to take your next step.
How preimplantation genetic testing supports gender selection
The basics of preimplantation genetic testing for aneuploidy
Preimplantation genetic testing – often referred to as PGT – is one of the most reliable tools we have in IVF today. By analysing the cells of an embryo before implantation, it’s possible to detect chromosomal abnormalities or genetic diseases early on. This not only helps improve IVF outcomes but also allows intended parents to know the sex of the embryo in advance.
Specifically, preimplantation genetic testing for aneuploidy (PGT-A) is used to screen embryos for the correct number of chromosomes. Healthy embryos have the best chance of developing into a successful pregnancy – and as part of this process, the sex of the embryo is also identified.
When genetic screening becomes a gender selection method
For some, this information is vital to avoid genetic disorders that are passed on through sex-linked chromosomes. For others, preconception sex selection is a way to create gender variety in the family – especially for those who already have multiple children of the same sex. In both cases, the use of PGT is not only about choosing – but about understanding.
While genetic screening is primarily designed to improve embryo quality and pregnancy success, it also provides a scientifically grounded and accurate method of gender selection. That’s why the committee of the American Society for Reproductive Medicine recognises PGT as an established part of reproductive care – especially when it’s used to detect conditions rather than solely to enable sex selection.
From sperm to embryo: where sex selection may happen
Sperm sorting versus embryo testing – what works better?
In earlier stages of assisted reproductive care, sperm sorting was considered a potential technique for influencing the outcome of a child’s sex. The method separates sperm cells carrying X or Y chromosomes, with the intention of increasing the likelihood of a male or female embryo. One such method, microsort gender selection, gained attention but was never approved by the FDA due to low success rates and inconsistent results.
While these approaches still exist, they are no longer regarded as an accurate gender selection method. The number of IVF cycles using such techniques has declined significantly as clinics increasingly rely on more advanced and reliable tools like preimplantation genetic testing.
Why genetic testing is more reliable than sperm-based methods
Modern IVF offers more than just choice – it offers precision. Genetic testing at the embryo level ensures that only healthy embryos are considered for transfer, and it provides knowledge of embryo sex at a much more accurate level than sperm-based methods ever could. This shift from preconception techniques to embryo-level diagnostics reflects the development of preimplantation genetic testing and its growing role in improving outcomes for patients requiring IVF who undergo PGT-A.
In addition to improving the chances of a healthy pregnancy, this approach also supports the ethical and medical framework defined by the ethics committee of the American Society for Reproductive Medicine. Their committee opinion notes that while practices enabling sex selection may exist, the focus must remain on health, autonomy and informed decision-making.
AI in embryo selection: the next leap in reproductive technology
How artificial intelligence may improve IVF outcomes
In the world of reproductive medicine, artificial intelligence is opening new doors. AI-powered tools are now being used to analyse embryo development in ways that are faster, more consistent, and sometimes even more accurate than the human eye. These systems help embryologists identify the embryos with the highest potential – based on thousands of data points gathered from time-lapse imaging and cell behaviour patterns.
This level of detail supports more informed embryo selection for transfer, and it has the potential to significantly improve IVF results for many patients. The integration of AI into the IVF process reflects a broader trend in assisted reproductive technologies, where machine learning supports complex medical decisions with precision and speed.
The growing role of preimplantation genetic screening
While AI can assess embryo quality based on physical development, it becomes even more powerful when combined with preimplantation genetic screening. This screening process – often known as PGS – identifies chromosomal imbalances that could lead to failed implantation or miscarriage.
By combining morphological data from AI tools with the genetic insights from PGS or PGT-A, clinics can create a highly personalised embryo profile. This not only improves the chances of success but also contributes to accurate gender selection in IVF cases where families are seeking gender variety. The purpose of sex selection, when integrated carefully and ethically, aligns with the broader goals of reproductive freedom and patient-centred care.
Microsort gender selection – and why we don’t recommend it
Poor success rates and no FDA approval
Microsort gender selection was once marketed as a non-invasive way to increase the chances of conceiving a child of a specific sex by separating X- and Y-bearing sperm cells. While the concept seemed appealing due to its simplicity, it has never been approved by the FDA and is not recognised by major professional bodies like the American Society for Reproductive Medicine or the Society for Assisted Reproductive Technology.
The primary reason lies in the lack of scientific validation and poor success rates compared to modern alternatives. In many cases, sperm sorting methods like Microsort have shown inconsistent results and raised concerns about safety, effectiveness and reliability – particularly when compared to the results seen with preimplantation genetic testing.
Why this gender selection method is not part of best practices
One of the main issues with sperm-based techniques is the lack thereof on embryo selection itself. These methods attempt to influence outcomes without any direct insight into embryo health or chromosomal balance. For this reason, they are not considered a safe or accurate gender selection procedure.
When patients are undergoing IVF, the goal should always be to prioritise healthy embryos – which is only possible through genetic testing. Using sperm sorting as a shortcut for selecting the sex of an embryo introduces unnecessary risks and is no longer in line with current medical practices enabling sex selection. For couples seeking gender variety, it’s essential to rely on proven technologies that are supported by a systematic review and meta-analysis of real outcomes, not hope-based solutions.
Finding the right support for your IVF gender selection journey
How to find clinics that offer advanced genetic testing
Choosing a fertility clinic is more than just comparing prices or scheduling an appointment. When it comes to IVF treatment combined with gender selection, it's important to understand which clinics offer advanced technologies, transparent communication, and ethical practices. Look for clinics that apply preimplantation genetic testing in line with international standards and are experienced in embryo selection based on genetic and chromosomal data.
While we don't recommend specific institutions, we encourage you to seek medical teams that work with certified laboratories and follow the guidance of organisations like the American Society for Reproductive Medicine and the Society for Assisted Reproductive Technology. Their committee opinion helps define responsible approaches in assisted reproductive care.
Why expert guidance matters when choosing a gender selection method
Whether you're starting your IVF journey or returning after previous experiences, personalised guidance can help you feel more confident. It’s not just about selecting the sex – it’s about understanding your options, asking the right questions, and finding professionals who listen to your needs.
A supportive advisor can help you assess whether you have a medical or personal indication for IVF with PGD, explain the benefits and limitations of each gender selection method, and ensure your values align with the procedure being offered. In an environment where reproductive technologies are advancing rapidly, being informed is key to feeling empowered.
" Reproductive freedom means making informed choices – with clarity, compassion, and the best technology available."
Conclusion: the future of reproductive choice and genetic precision
What we’ve learned about technology in embryo selection
The development of preimplantation genetic testing has changed the way we approach IVF. What was once a hopeful but uncertain process has become increasingly precise – guided by data, supported by innovation, and shaped by a clearer understanding of genetics. IVF gender selection today relies on the combination of laboratory expertise, ethical frameworks, and the use of AI-supported embryo evaluation.
With more IVF cycles using PGT, the possibilities for selecting the sex of the embryo – and ensuring its health – have never been greater. For patients requiring IVF who undergo PGT-A, this process offers clarity and confidence, helping them move forward with informed decisions.
How innovation is transforming reproductive freedom
We’re entering a time when reproductive medicine not only supports fertility but also honours individual needs, including the desire for gender variety in the family. While the reasons to couples seeking gender selection may vary, the technology behind it remains grounded in science. From accurate gender selection to minimising the risk of genetic disease, these tools are reshaping what’s possible.
Still, it's important to acknowledge that gender discrimination may exist in some contexts, and significant gender injustice must be avoided. The ethics committee of the American Society for Reproductive Medicine emphasises that practices enabling sex selection may be acceptable when they support patient autonomy and reproductive liberty – but never when they reinforce pressure to conform to gender norms.
As we move forward, the challenge is not only to improve IVF but to ensure that every step of the process remains patient-centred, responsible and transparent. With each breakthrough, we get closer to a future where selecting the sex is not a question of controversy – but of choice, care and knowledge.
Download our guide on IVF destinations in Europe
Planning an IVF journey can feel overwhelming – especially when you're looking for specific options like gender selection. Legal frameworks, available technologies, and clinic standards vary widely between countries, and reliable information isn't always easy to find.
To help you get started, we’ve created a practical and easy-to-read guide that explains where sex selection may be available and what you can expect in terms of success rates and costs. It also includes a real-life example using preimplantation genetic testing for aneuploidy – so you can get a clearer idea of what such a treatment might involve, without any pressure or clinic recommendation.
If you’re considering IVF with PGD or simply want to understand your options before moving forward, this guide is the perfect place to begin. It was designed to support couples seeking gender selection as well as solo parents – with respect, privacy, and transparency.
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