How Artificial Intelligence Is Changing Embryo and Egg Assessment: A Look at CHLOE by Fairtility

If you're currently exploring IVF options abroad, you've probably come across some new terms and technologies that sound exciting – but also a bit overwhelming. One name that keeps popping up in modern fertility clinics is “CHLOE.” At first, it might sound like just a pretty name. But CHLOE actually stands for Cultivating Human Life through Optimal Embryos – and it’s one of the most promising innovations in fertility care today.

So what exactly is CHLOE? And what does it mean for you – especially if you're considering treatments like egg donation, embryo donation, or IVF with gender selection?

In this blog, we’ll take a closer look at how CHLOE works, how it’s being used in real IVF labs around the world, and why more and more clinics are choosing to rely on this transparent AI technology to support embryo and egg assessment.

Our goal is to explain everything in simple, clear terms – so you can feel informed and confident when making decisions about your own fertility journey.

What Is CHLOE and How Does It Work in IVF Labs?

CHLOE is not just another lab gadget. It’s a smart, AI-powered assistant that helps embryologists do what they already do – just with more precision, more consistency, and more information than ever before. Think of it as an extra set of expert eyes that never get tired, miss a detail, or lose focus.

In IVF labs, CHLOE is used to monitor embryos from the very first moments after fertilization. Normally, embryos are placed into special time-lapse incubators that capture images 24/7 without disturbing the delicate environment. CHLOE then analyzes this massive amount of data – frame by frame, moment by moment – looking at subtle changes in timing, movement, shape, and other developmental markers.

This allows embryologists to get a much deeper understanding of how each embryo is developing. And because CHLOE is trained on millions of data points from real IVF cases around the world, it’s able to spot patterns and details that are nearly impossible to catch with the human eye alone.

But CHLOE doesn’t make decisions on its own. It supports the professionals. Embryologists still review everything personally – they simply use CHLOE’s insights to make more informed, more confident choices.

CHLOE EQ and CHLOE OQ: Supporting Embryo and Egg Assessment

CHLOE isn’t just one tool – it’s a full platform with different modules that support various stages of the IVF process. Two of the most important ones are CHLOE EQ and CHLOE OQ.

CHLOE EQ stands for Embryo Quality Insights. It helps embryologists assess the quality and viability of embryos based on how they develop in the first five days after fertilization. CHLOE watches and analyzes the entire development process without ever removing the embryos from their incubator. Every tiny change – from the first cell division to blastocyst formation – is tracked and time-stamped. CHLOE EQ uses this data to provide detailed insights that can support the decision on which embryo might offer the best chance for implantation.

Then there’s CHLOE OQ, which focuses on egg quality. This is especially relevant if you’re freezing your eggs, using donor eggs, or planning a cycle where every egg counts. Until recently, egg quality was mostly judged by eye – and based on experience. CHLOE OQ changes that. It looks at high-resolution images of each egg and provides a detailed, objective evaluation. This helps clinics plan better, and gives you more realistic expectations about what your frozen or donated eggs might offer in the future.

In both cases, the goal is the same: to make smarter, more personalized decisions – and to give you as the patient more clarity and confidence along the way.

What Are the Real Benefits of CHLOE for You as a Patient?

Let’s be honest: when you’re going through IVF, so much feels out of your control. You trust the clinic, the lab, the process – but at times, you might feel like you don’t really know what’s going on behind the scenes. That’s exactly where CHLOE comes in.

CHLOE doesn’t change the actual treatment – but it changes the way decisions are made. And that can make all the difference.

Here’s how it can support you on your journey:

More transparency and clarity
CHLOE helps embryologists make decisions based on clear, consistent, data-driven insights. For you, that means more trust in the process – and fewer unanswered questions.

Stronger communication with your clinic
If your clinic offers the CHLOE Embryo Development Viewer™, you may even be able to see how your embryos are developing – in real time. Alongside this, you might receive a Cycle Report that helps you understand what’s happening day by day in the lab.

Better outcomes, fewer cycles
By identifying the embryos or eggs with the highest potential, CHLOE may help reduce the number of unsuccessful transfers. That means fewer hormone treatments, fewer emotional ups and downs, and potentially less financial stress.

Support in complex cases
If you’ve had previous IVF failures, are over 35, or are using donated eggs or embryos, CHLOE adds another layer of support. It’s especially helpful when decisions need to be made quickly or when every detail counts.

In short: CHLOE helps the team in the lab see more, understand more – and make better decisions together with you. And that can feel incredibly empowering.

Why Transparency in AI Matters

Artificial intelligence can sound a bit intimidating at first. You might wonder: Can I really trust a machine to help decide which embryo to transfer? And that’s a completely valid question.

What makes CHLOE different from many other AI tools is one key thing: transparency.

Unlike so-called “black box” systems, where even experts can’t fully explain how a decision was made, CHLOE is designed to be open and understandable. It’s not just about what the AI decides – it’s about why it makes that decision.

That’s important for two reasons:

First, it gives your fertility team the ability to double-check and interpret the data in human terms. CHLOE doesn’t replace anyone – it supports the people who care for you with extra insights they can actually explain.

Second, it gives you more confidence. When your clinic can show you how your embryos developed, what was observed, and why certain choices were made, the whole experience becomes more transparent and less mysterious. You feel included – and more in control of your own journey.

Transparency also helps reduce the risk of bias. CHLOE is trained on a large and diverse dataset of real IVF cases from around the world, which helps make its predictions more accurate and fair over time.

How Accurate Is CHLOE – and Has It Been Scientifically Proven?

You might be wondering: Sounds great – but does it really work?

Fair question. And the short answer is: yes, CHLOE has been extensively tested and validated in real IVF labs. It’s not just a nice idea or a futuristic concept – it’s already in use, and the data speaks for itself.

CHLOE Embryo Quality Insights (CHLOE EQ™) has shown a blastocyst prediction accuracy of 96% and an implantation prediction accuracy of 73%. That means the system is able to reliably identify which embryos are most likely to reach the blastocyst stage – and which ones have the highest chances of implantation.

CHLOE’s effectiveness has also been confirmed in multiple peer-reviewed studies published in top journals like Human Reproduction and Fertility & Sterility. More than 80 abstracts have been presented at major fertility conferences like ESHRE and ASRM.

It’s also worth noting: CHLOE has been recognized with the 2023 MedTech Breakthrough Award for Women’s Health Innovation – which is a strong signal that this technology is truly making a difference in reproductive care.

So yes – CHLOE is not only safe and approved, but also backed by solid clinical research.

Curious to Know If CHLOE Could Be Part of Your IVF Journey?

Every fertility journey is different – and understanding which technologies a clinic uses can make a big difference in how confident you feel moving forward. If you're exploring treatment options abroad and want to know more about where CHLOE is used, or how to find a clinic that offers AI-supported embryo evaluation, I'm here for you.

I’ve helped hundreds of women understand the differences between IVF clinics in Europe and supported them in choosing the right option – without pressure, and with full discretion.

You can book a consultation with me to explore your options and receive clear, honest guidance on your next step.

👉 Click here to get your free guide to IVF destinations in Europe

Wishing you strength, clarity, and the right support on your path to parenthood.

With care,

Nathalie Wiederkehr

Specialised in IVF with gender selection and treatments abroad